The following article was written by William Faloon, editor of Life Extension Magazine. Mr. Faloon has been a tireless advocate for consumers in the area of health. This article is so important, we felt it imperative to publish it in its entirety so that you can see what the government is up to when it comes to restricting your access to information on natural, non-pharmaceutical ways to create health and well-being.
FDA Says Walnuts Are Illegal Drugs
by William Faloon
Life Extension® has published 57 articles that describe the health benefits of walnuts.
Some of this same scientific data was featured on the website of Diamond Foods, Inc., a distributor of packaged walnuts.
Last year the FDA determined that walnuts sold by Diamond Foods cannot be legally marketed because the walnuts “are not generally recognized as safe and effective” for the medical conditions referenced on Diamond Foods’s website.
According to the FDA, these walnuts were classified as “drugs” and the “unauthorized health claims” cause them to become “misbranded,” thus subjecting them to government “seizure or injunction.”
Diamond Foods capitulated and removed statements about the health benefits of walnuts from its website.
Let’s take a look at the science supporting the consumption of walnuts to see what the FDA censored…and what you can do to stop it in the future!
Eating Walnuts Cuts Heart Disease Risk
Ingesting nuts used to be considered unhealthy because of their high fat content. This misconception has changed over the past 18 years as human studies have revealed sharply reduced incidence of heart disease in those who consume walnuts.(1-12)
Unlike some nuts, walnuts provide a unique blend of polyunsaturated fatty acids (including omega-3s), along with nutrients like gamma-tocopherol that have demonstrated heart health benefits.(13-24)
The March 4, 1993, issue of the New England Journal of Medicine published the first clinical study showing significant reductions in dangerous LDL and improvement in the lipoprotein profile in response to moderate consumption of walnuts.14 Later studies revealed that walnuts improve endothelial function in ways that are independent of cholesterol reduction.(1, 25-27)
One study published by the American Heart Association journal Circulation on April 6, 2004, showed a 64% improvement in a measurement of endothelial function when walnuts were substituted for other fats in a Mediterranean diet.(1)
As most Life Extension members are aware, the underlying cause of atherosclerosis is progressive endothelial dysfunction.(28) Walnuts contain a variety of nutrients including arginine, polyphenols, and omega-3s that support the inner arterial lining and guard against abnormal platelet aggregation.(2,13,29-31) These favorable biological effects explain why walnut consumption confers protection against coronary artery disease.
The US National Library of Medicine database contains no fewer than 35 peer-reviewed published papers supporting a claim that ingesting walnuts improves vascular health and may reduce heart attack risk.
FDA Ignores the Science
The federal agency responsible for protecting the health of the American public views this differently.
On our website, we reprint the FDA’s entire warning letter to Diamond Foods. Nowhere in this bureaucratic albatross is there any discussion of the science cited by Diamond Foods to support their health claims.
Instead, the FDA’s language resembles that of an out-of-control police state where tyranny reins over rationality. To enable you to recognize the absurdity of all of this, I excerpted a few paragraphs from the FDA’s warning letter to Diamond Foods starting below.(32)
Excerpt from FDA Letter
“Based on our review, we have concluded that your walnut products are in violation of the Federal Food, Drug, and Cosmetic Act (the Act) and the applicable regulations in Title 21, Code of Federal Regulations (21 CFR).
“Based on claims made on your firm’s website, we have determined that your walnut products are promoted for conditions that cause them to be drugs because these products are intended for use in the prevention, mitigation, and treatment of disease.
“Because of these intended uses, your walnut products are drugs within the meaning of section 201 (g)(1)(B) of the Act [21 U.S.C. § 321(g)(B)]. Your walnut products are also new drugs under section 201(p) of the Act [21 U.S.C. § 321(p)] because they are not generally recognized as safe and effective for the above referenced conditions. Therefore, under section 505(a) of the Act [21 U.S.C. § 355(a)], they may not be legally marketed with the above claims in the United States without an approved new drug application.
“Additionally, your walnut products are offered for conditions that are not amenable to self-diagnosis and treatment by individuals who are not medical practitioners; therefore, adequate directions for use cannot be written so that a layperson can use these drugs safely for their intended purposes. Thus, your walnut products are also misbranded under section 502(f)(1) of the Act, in that the labeling for these drugs fails to bear adequate directions for use [21 U.S.C. § 352(f)(1)].”
This verbiage makes it clear that the FDA does not even consider the underlying science when censoring truthful, non-misleading health claims. The chilling effect on the ability of consumers to discover lifesaving medical information is a wake-up call for all who recognize the ramifications of this latest act of FDA malfeasance.
What the FDA Allows You to Hear
The number of people logging on to the website of Diamond Foods was miniscule. I suspect that before the FDA took this draconian action, hardly anyone even knew this website existed.
What the public hears loud and clear, however, are endless advertisements for artery-clogging junk foods. Fast food chains relentlessly promote their 99-cent double-cheese burger as being bigger than their rivals. These advertisements induce many consumers to salivate for these toxic calories that are a contributing cause of coronary artery disease. Yet the FDA does not utter a peep in suggesting that their advertising be curtailed.
On the contrary, the FDA has issued waves of warning letters to companies making foods (pomegranate juice, green tea, and walnuts) that protect against atherosclerosis.(1,32-36) The FDA is blatantly demanding that these companies stop informing the public about the scientifically validated health benefits these foods provide.
The FDA obviously does not want the public to discover that they can reduce their risk of age-related disease by consuming healthy foods. They prefer consumers only learn about mass-marketed garbage foods that shorten life span by increasing degenerative disease risk.
FDA Allows Potato Chips to Be Advertised as “Heart Healthy”
Frito-Lay® is a subsidiary of the PepsiCo, Inc., makers of Pepsi-Cola. Frito-Lay® sells $12 billion a year of products that include:
Lays® Potato Chips
Doritos®
Tostitos®
Cheetos®
Fritos®
You might not associate these mostly-fried snack foods as being good for you, but the FDA has no problem allowing the Frito-Lay® website to state the following:
“Frito-Lay® snacks start with real farm-grown ingredients. You might be surprised at how much good stuff goes into your favorite snack. Good stuff like potatoes, which naturally contain vitamin C and essential minerals. Or corn, one of the world’s most popular grains, packed with thiamin, vitamin B6, and phosphorous—all necessary for healthy bones, teeth, nerves and muscles.
“And it’s not just the obvious ingredients. Our all-natural sunflower, corn and soybean oils contain good polyunsaturated and monounsaturated fats, which help lower total and LDL ‘bad’ cholesterol and maintain HDL ‘good’ cholesterol levels, which can support a healthy heart. Even salt, when eaten in moderation as part of a balanced diet, is essential for the body.”(37)
Wow! Based on what Frito-Lay® is allowed to state, it sounds like we should be living on these snacks. Who would want to ingest walnuts, pomegranate, or green tea (which the FDA is attacking) when these fat calorie-laden, mostly-fried carbohydrates are so widely available?
According to the Frito Lay® website, Lays® potato chips are “heart healthy” because the level of saturated fat was reduced and replaced with sunflower oil.(38) Scientific studies do show that when a polyunsaturated fat (like sunflower oil) is substituted for saturated fat, favorable changes in blood cholesterol occur.(39)
Fatally omitted from the Frito-Lay® website is the fact that sunflower oil supplies lots of omega-6 fats, but no omega-3s.40 The American diet already contains too many omega-6 fats and woefully inadequate omega-3s.
Excess omega-6 fats in the diet in the absence of adequate omega-3s produce devastating effects, including the production of pro-inflammatory compounds that contribute to virtually every age-related disease, including atherosclerosis.(41-45)
For the FDA to allow Frito-Lay® to pretend there are heart benefits to ingesting their unhealthy snack products, while censoring the ability of walnut companies to make scientifically substantiated claims, is tantamount to treason against the health of the American public.
Don’t Forget the Acrylamides
When carbohydrate foods are cooked at high temperature (as occurs when potatoes are fried in sunflower oil to make potato chips), a toxic compound called acrylamide is formed.(46)
According to the National Cancer Institute, “acrylamide is considered to be a mutagen and a probable human carcinogen, based mainly on studies in laboratory animals. Scientists do not yet know with any certainty whether the levels of acrylamide typically found in some foods pose a health risk for humans.”(47)
In response to these kinds of concerns, the FDA funded a massive study to ascertain the acrylamide content of various foods. The FDA found that potato chips and other fried carbohydrate foods were especially high in acrylamides.(48)
The FDA, however, has not stopped companies selling high acrylamide–containing fried carbohydrates from promoting these foods as “healthy.”
Pharmaceutical Companies Benefit From FDA’s Misdeeds
As the aging population develops coronary atherosclerosis, pharmaceutical companies stand to reap tens of billions of dollars each year in profits. An obstacle standing in their way is scientific evidence showing that a healthy diet can prevent heart disease from developing in many people.
It is thus in the economic interests of pharmaceutical giants that the FDA forcibly censor the ability of companies making heart healthy foods to inform the public of the underlying science. The fewer consumers who know the facts about walnuts, pomegranate, and green tea, the greater the demand will be for expensive cardiac drugs, stents, and coronary bypass procedures.
Once again, the FDA overtly functions to enrich Big Pharma, while the public shoulders the financial burden of today’s health care cost crisis.
In this particular case, however, processed food companies also stand to profit from the FDA’s attacks on healthy foods as competition from walnut growers is stifled.
FDA/FTC Wants More Control Over What You Are Allowed to Learn
The FDA and FTC (Federal Trade Commission) are proposing new regulations that will stifle the ability of natural food companies to disseminate scientific research findings.
One proposal being discussed within the FTC would require that supplement companies conduct studies analogous to what the FDA requires to approve new drugs. In a perfect world, Life Extension would agree with some of the FTC’s objectives. As far as we are concerned, the more scientific research to validate a health claim, the better.
The reality is that natural foods do not carry high prescription drug price markups, so it would be economically impossible to conduct the same kinds of voluminous clinical studies as pharmaceutical companies do. As readers of this column know, many of the clinical studies the FDA relies on to approve new drugs are fraudulent to begin with. So even if it were feasible to conduct more clinical research on foods and supplements, that still does not guarantee the precise accuracy the FTC is seeking.
If these agency proposals are enacted, consumers will be barred from learning about new ways to protect their health until a food or nutrient meets stringent new requirements. A look at the warning letter the FDA sent to Diamond Foods is a frightening example of how scientific information can be harshly censored by unelected bureaucrats.
If anyone still thinks that federal agencies like the FDA protect the public, this proclamation that healthy foods are illegal drugs exposes the government’s sordid charade.
CHILLING EFFECT ON INNOVATION
Headquartered in Stockton, California, Diamond Foods is a processor and marketer of nuts, with distribution in over 80% of US supermarkets. Most of Diamond’s 1,700 walnut growers are family farmers with orchards in the heartland of California’s Central Valley. Their association with Diamond guarantees a market for their crops and provides the company with high-quality walnuts.
In response to independent scientific studies validating the health benefits of walnuts, Diamond Foods made financial investments to educate the public and supply them with walnuts. With one misguided letter issued by the FDA, all of Diamond Foods’s good work was undone.
This kind of bureaucratic tyranny sends a strong signal to the food industry not to innovate in a way that informs the public about foods that protect against disease. While consumers increasingly reach for healthier dietary choices, the federal government wants to deny food companies the ability to convey findings from scientific studies about their products.
Companies That Sell Healthy Foods Try to Fight Back
The combined sales of the companies attacked by the FDA are only a fraction of those of food giant Frito-Lay®. Yet some of these companies are fighting back against the FDA’s absurd position that it is illegal to disseminate scientific research showing the favorable effects these foods produce in the body. The makers of pomegranate juice, for example, have sued the FTC for censoring their First Amendment right to communicate scientific information to the public.
As a consumer, you should be outraged that disease-promoting foods are protected by the federal government, while nutritious foods are censored. There is no scientific rationale for the FDA to do this. On the contrary, the dangerous foods ubiquitously advertised in the media are replacing cigarettes as the leading killers in modern society.
The federal government is heavily lobbied by companies selling processed foods. As Life Extension revealed long ago, an insidious activity of lobbyists is to incite federal agencies and prosecutors to eliminate free competition in the marketplace.
The simple fact is that walnuts are healthy to eat, while carbohydrates fried in fat are not. The FDA permits companies selling disease-promoting foods to deceive the public, while it suppresses the dissemination of peer-reviewed scientific information about healthy foods.
Now the Good News…
On April 5, 2011, a bipartisan bill was introduced into the House of Representatives called the Free Speech About Science Act (H.R. 1364). This landmark legislation protects basic free speech rights, ends censorship of science, and enables the natural health products community to share peer-reviewed scientific findings with the public.
The Free Speech About Science bill has the potential to transform medical practice by educating the public about the real science behind natural health.
For this very reason, the bill will encounter opposition. It will be opposed by the FDA since it restricts their ability to censor the dissemination of published scientific data. It will be opposed by drug companies fearing competition from natural health approaches based on diet, dietary supplements, and lifestyle.
The public, on the other hand, wants access to credible information they can use to make wise dietary choices. Please don’t let special interests stop this bill.
I ask that each of you log on to our Legislative Action Website (www.lef.org/lac) that enables you to conveniently email and ask your Representative to co-sponsor the Free Speech About Science Act (H.R. 1364).
Passage of the Free Speech About Science Act will stop federal agencies from squandering tax dollars censoring what you are allowed to learn about health-promoting foods.
Our Legislative Action Website provides you direct contact with your Representative to let them know that you want H.R. 1364 (Free Speech About Science Act) enacted into law.
The letter that follows is what you can easily send to your Representative by logging on to www.lef.org/lac.
To the Honorable:
Please co-sponsor the Free Speech About Science Act (H.R. 1364).
This is critical because more Americans are taking charge of their personal health—determined to improve their diets and emphasize preventive care in order to stay or get healthy. Consumers are looking for reliable information backed by legitimate scientific research to assist in making informed choices.
But FDA regulations currently prohibit producers of food from referring to any scientific study documenting the potential effect of the substance on a health condition. Violation of this ban can result in the FDA declaring common foods to be “unapproved drugs,” the sale of which is subject to large fines and jail. Even cherry growers have been told by the FDA that they face jail if they link to Harvard and other studies outlining the health benefits of cherries for gout or arthritis pain. The FDA has taken these actions against walnut growers as well.
The Free Speech About Science Act of 2011 provides a limited and carefully targeted change to FDA regulations so that legitimate, peer-reviewed, scientific studies may be referenced by manufacturers and producers without converting a healthy food into an unapproved drug. The bill amends the appropriate sections of current law to allow the flow of legitimate scientific and educational information while still giving the FDA and FTC the right to take action against misleading information and against false and unsubstantiated claims.
The Free Speech About Science Act:
(1) Provides a clear definition of the types of research that may be referenced by growers and manufacturers;
(2) Ensures that referencing such research does not convert a food or dietary supplement into an “unapproved [and therefore illegal] new drug;” and
(3) Does not in any way limit FDA and FTC authority to pursue any fraudulent and misleading statements.
All of us, no matter what our party or views about healthcare, are coming to see the importance of preventive care, or preventing illnesses before they start. Diet, dietary supplements, and lifestyle play a large role in prevention. The FDA should be at the forefront of this. Instead, it is blocking producers from giving consumers truthful scientific information about healthy foods.
The FDA responds that cherries and the like should be subjected to the full FDA approval process. But this would cost as much as a billion dollars. With few exceptions, it is not possible for food producers to assume such costs for natural and therefore non-patentable products.
This is the great Catch-22 of contemporary American medicine. The FDA should find a less expensive way to “vet” natural products. Respected university research suggests that in many cases natural products are safer, more efficacious, and of course much cheaper than drugs. In the meantime, we should modify the law to at least let producers cite valid peer-reviewed science.
Please help me gain the information I need to stay healthy; co-sponsor the Free Speech About Science Act (H.R. 1364)!
References
1. Ros E, Nunez I, Perez-Heras A, et al. A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. Circulation. 2004 Apr 6;109(13):1609-14.
2. Feldman EB. The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J Nutr. 2002 May;132(5):1062S-1101S.
3. Blomhoff R, Carlsen MH, Andersen LF, Jacobs DR Jr. Health benefits of nuts: potential role of antioxidants. Br J Nutr. 2006 Nov;96 Suppl 2:S52-60.
4. Mozaffarian D. Does alpha-linolenic acid intake reduce the risk of coronary heart disease? A review of the evidence. Altern Ther Health Med. 2005 May-Jun;11(3):24-30; quiz 31, 79.
5. Zhao G, Etherton TD, Martin KR, West SG, Gillies PJ, Kris-Etherton PM. Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr. 2004 Nov;134(11):2991-7.
6. Tapsell LC, Gillen LJ, Patch CS, Batterham M, Owen A, Baré M, Kennedy M. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care. 2004 Dec;27(12):2777-83.
7. West SG, Boseka L, Wagner P. Alpha-linolenic acid from walnuts and flax increases flow-mediated dilation of the brachial artery in a dose-dependent fashion. Poster presented at the American Heart Association’s 5th Annual Conference on Arteriosclerosis, Thrombosis, and Vascular Biology. San Francisco, CA: May 6, 2004.
8. Iwamoto M, Imaizumi K, Sato M, Hirooka Y, Sakai K, Takeshita A, Kono M. Serum lipid profiles in Japanese women and men during consumption of walnuts. Eur JClin Nutr. 2002 Jul;56(7):629-37.
9. Morgan JM, Horton K, Reese D, et al. Effects of walnut consumption as part of a low-fat, low-cholesterol diet on serum cardiovascular risk factors. Int J Vit Nutr Research. 2002 Oct;72(5):341-7.
10. Hu FB, Stampfer MJ, Manson JE, et al. Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study. BMJ. 1998 Nov 14;317(7169):1341-5.
11. Chisholm A, Mann J, Skeaff M, et al. A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur J Clin Nutr. 1998 Jan;52(1):12-6.
12. de Lorgeril M, Renaud S, Mamelle N, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet. 1994 Jun 11;343(8911):1454-9.
13. Maguire LS, O’Sullivan SM, Galvin K, O’Connor TP, O’Brien NM. Fatty acid profile, tocopherol, squalene and phytosterol content of walnuts, almonds, peanuts, hazelnuts and the macadamia nut. Int J Food Sci Nutr. 2004 May;55(3):171-8.
14. Sabate J, Fraser GE, Burke K, Knutsen SF, Bennett H, Lindsted KD. Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med. 1993 Mar 4;328(9):603-7.
15. Zambon D, Sabate J, Munoz S, et al. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann Intern Med. 2000 Apr 4;132(7):538-46.
16. Iwamoto M, Imaizumi K, Sato M, et al. Serum lipid profiles in Japanese women and men during consumption of walnuts. Eur J Clin Nutr. 2002 Jul;56(7):629-37.
17. Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr. 1999 Sep;70(3 Suppl):560S-569S.
18. Hu FB, Stampfer MJ. Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence. Curr Atheroscler Rep. 1999 Nov;1(3):204-9.
19. Zibaeenezhad MJ, Rezaiezadeh M, Mowla A, Ayatollahi SM, Panjehshahin MR. Antihypertriglyceridemic effect of walnut oil. Angiology. 2003 Jul-Aug;54(4):411-4.
20. Almario RU, Vonghavaravat V, Wong R, Kasim-Karakas SE. Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. Am J Clin Nutr. 2001 Jul;74(1):72-9.
21. Anderson KJ, Teuber SS, Gobeille A, Cremin P, Waterhouse AL, Steinberg FM. Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation. J Nutr. 2001 Nov;131(11):2837-42.
22. Singh I, Turner AH, Sinclair AJ, Li D, Hawley JA. Effects of gamma-tocopherol supplementation on thrombotic risk factors. Asia Pac J Clin Nutr. 2007;16(3):422-8.
23. McCarty MF. Gamma-tocopherol may promote effective no synthase function by protecting tetrahydrobiopterin from peroxynitrite. Med Hypotheses. 2007;69(6):1367-70.
24. Park SK, Page GP, Kim K, et al. alpha- and gamma-Tocopherol prevent age-related transcriptional alterations in the heart and brain of mice. J Nutr. 2008 Jun;138(6):1010-8.
25. Cortés B, Núñez I, Cofán M, et al. Acute effects of high-fat meals enriched with walnuts or olive oil on postprandial endothelial function. J Am Coll Cardiol. 2006 Oct 17;48(8):1666-71.
26. Ros E, Mataix J. Fatty acid composition of nuts—implications for cardiovascular health. Br J Nutr. 2006 Nov;96 Suppl 2:S29-35.
27. Ma Y, Njike VY, Millet J, et al. Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial. Diabetes Care. 2010 Feb;33(2):227-32.
28. Le Brocq M, Leslie SJ, Milliken P, Megson IL. Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities. Antioxid Redox Signal. 2008 Sep;10(9):1631-74.
29. Ros E. Nuts and novel biomarkers of cardiovascular disease. Am J Clin Nutr. 2009 May;89(5):1649S-56S.
30. Feldman EB. The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J Nutr. 2002 May;132(5):1062S-1101S.
31. Ristic-Medic D, Ristic G, Tepsic V. Alpha-linolenic acid and cardiovascular diseases. Med Pregl. 2003;56 Suppl 1:19-25.
32. Available at: http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm202825.htm. Accessed March 26, 2010.
33. Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr. 2004 Jun;23(3):423-33.
34. Oyama J, Maeda T, Kouzuma K, et al. Green tea catechins improve human forearm endothelial dysfunction and have antiatherosclerotic effects in smokers. Circ J. 2010 Mar;74(3):578-88.
35. Available at: http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm202785.htm. Accessed April 11, 2011.
36. Available at: http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm224509.htm. Accessed April 11, 2011.
37. Available at: http://www.fritolay.com/your-health/whats-in-our-snacks.html. Accessed March 25, 2010.
38. Available at: http://www.fritolay.com/about-us/press-release-20060503.html. March 25, 2010.
39. Jakobsen MU, O’Reilly EJ, Heitmann BL, et al. Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr. 2009 May;89(5):1425-32.
40. Scherr C, Ribeiro JP. Fat content of dairy products, eggs, margarines and oils: implications for atherosclerosis. Arq Bras Cardiol. 2010 Jul;95(1):55-60.
41. Available at: http://www.kedu.us/Ask%20the%20Doctor/omega%203%20cardiovascular.pdf. Accessed March 29, 2010.
42. Simopoulos AP. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood). 2008 Jun;233(6):674-88.
43. Okuyama H, Kobayashi T, Watanabe S. Dietary fatty acids–the N-6/N-3 balance and chronic elderly diseases. Excess linoleic acid and relative N-3 deficiency syndrome seen in Japan. Prog Lipid Res. 1996 Dec;35(4):409-57.
44. Kiecolt-Glaser JK, Belury MA, Porter K, et al. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. Psychosom Med. 2007 Apr;69(3):217-24.
45. Guebre-Egziabher F, Rabasa-Lhoret R, Bonnet F, et al. Nutritional intervention to reduce the n-6/n-3 fatty acid ratio increases adiponectin concentration and fatty acid oxidation in healthy subjects. Eur J Clin Nutr. 2008 Nov;62(11):1287-93.
46. Jackson LS, Al-Taher F. Effects of consumer food preparation on acrylamide formation. Adv Exp Med Biol. 2005 561:447-65.
47. Available at: http://www.cancer.gov/cancertopics/factsheet/Risk/Fs3_96.pdf. Accessed April 11, 2010.
48. Available at: http://www.fda.gov/food/foodsafety/foodcontaminantsadulteration/chemicalcontaminants/acrylamide/ucm053569.htm. Accessed April 11, 2011.
